Advantage II Flea Prevention for Large Cats
Bayer Advantage II is a vet-recommended topical flea treatment and prevention designed for large cats weighing over 9 pounds. It works by killing fleas through direct contact, so fleas do not need to bite your cat to be eliminated. The treatment targets fleas at multiple life stages, helping to break the flea life cycle and control existing infestations while preventing new ones.
The liquid formulation is easy to apply, fragrance-free, and becomes waterproof within 24 hours. A single application begins working within 12 hours and provides protection for up to 30 days.
Key Features
- Kills fleas in all life stages
- Starts working in 12 hours
- Provides up to 30 days of protection
- Fragrance-free and waterproof after 24 hours
- Easy to apply topical solution
| Product Information |
|---|
| Form: Topical liquid |
| Application Frequency: Monthly |
| Protected Weight Range: Over 9 pounds |
| Duration of Protection: Up to 30 days |
FAQ
How long does Advantage II take to start working?
Advantage II starts working within 12 hours of application.
Does Advantage II work on all life stages of fleas?
Yes, Advantage II kills fleas at multiple life stages, including eggs, larvae, and adults.
Is the product safe for indoor cats?
Yes, Advantage II is effective for indoor cats as well, since fleas can be brought into homes by humans or other pets.

Emily Baker –
My cat has never had fleas since I started using Advantage II. The application is simple and the cat doesn’t seem to react to it. I’ve used it for three months now and haven’t seen any signs of fleas. It’s a reliable solution for large cats.
Gavin Chapman –
I was worried about the smell, but it’s fragrance-free and my cat didn’t show any discomfort. After one month, I noticed fewer flea bites and no new fleas. Works well for indoor cats too.
Frank Arnold –
My cat is over 10 pounds and this treatment has been effective. It’s easy to apply and the protection lasts the full month. No more scratching or flea-related stress for my cat.